About us
I1 RecLOH - YCAII a,b = 21,21
As we constantly improve and expand the Project, we will not forget our original mission, which was to investigate the shared ancestry of families that experienced the RecLOH mutation YCAII a,b=21,21. Original members of the former‘21,21' project who tested negative for both of the SNPs, Z58 and Z63 have been sub-grouped as M253>DF29* on the Y-DNA Results Page.
YCAIIa,b=21,21 is carried by numerous participants in the Z58+ and Z63+ sectors. A RecLOH(Recombinational Loss of Heterozygosity) event is "a type of mutation which occurs with DNA by recombination." From a pair of equivalent(homologous), but slightly different (heterozygous) segments, a pair of identical (homozygous) segments results.
Palindromic Panel tests have been performed by Family Tree DNA to determine the nature of the RecLOH events affecting the 21,21 members of this project. In particular, advanced marker DYF399X has proven to be a very good glimpse intothese events. They are listed below.
DYF399X results
A few notes: The results at the top belong to members of the former I1 RecLOH - YCAII a,b = 21,21 Project, otherwise AS generic I1 individuals. Highlights in yellow represent deviations from the modal (21t-22c-23c). The individual in green is a non-21,21 AS generic male, picked randomly as the control sample for the DYF399X tests. Individuals in blue are non-21,21 AS generic males whose standard marker values would indicate a close relationship to the 21,21's. DYF399X results demonstrate the apparent closeness of the individuals in blue to the 21,21's in the standard markers is but coincidental, as there is a consistent distance in the advanced marker results, despite the fact that the MRCA of these Ellis individuals seems to have lived earlier than the 1700's. Due to the consistency of these results, DYF399X results will be used to determine whether a 21,21 individual is in fact a descendant of the recLOH ancestor of the members of this I1 recLOH - YCAII a,b = 21,21 project.
German Group:
Jergens kit#7121 - Theodore Rogahn b.1/8/1840 - Pomerania DYF399X:21t-22c-23c
Italian Group:
Taravella kit#141065 - Taravella, Valledolmo, Sicily, DYF399X:21t-22c-23c
Iberian Group:
Salles Fernandes Silva Torres kit#148532 - Pedro Dias, b. c. 1560 - Mariz, Portugal DYF399X:20t-22c-23c
Gomes Torres kit#186618 - Pedro Dias, b. c. 1560 - Mariz, Portugal DYF399X:20t-22c-23c
Vieira kit#192543 DYF399X:20t-22c-22c
Torres kit#56147 - Anselmo Gonzalez Ruiz, b. c. 1856 - Puerto Rico DYF399X:21t-22c-21c
Gonzalez kit#178677 DYF399X:20t-22c-21c
British Group:
Frame kit#162603 - Andrew Frame, b. c. 1767 - Scotland DYF399X:20t-22c-23c
Frame kit#202230 - James Frame, b. c. 1661 - Scotland DYF399X:20t-22c-23c
Frame kit#193024 - John Frame, b. c. 1791 - 1844 - Scotland DYF399X:20t-23c-23c
Jobling kit#131250 - John Jopling DYF399X:20t-21c-23c
Frame kit#110709 - John Frame, b. c. 1777 - Lanark, Scotland DYF399X:21t-21c-23c
Frame kit#64529 - Robert Frame, b. c. 1705 - Scotland DYF399X:21t-22c-23c
Frame kit#84205 - Thomas Frame, b. c. 1640 - Durham, England DYF399X:21t-22c-23c
Frame kit#91065 - Thomas Frame, b. c. 1767 - Scotland DYF399X:21t-22c-23c
Frame kit#153309 - James Frame, b. c. 1776 - Scotland DYF399X:21t-22c-23c
Hamilton kit#8048 - John Hamilton, m. 10 Jul 1755 - Carluke, Scotland DYF399X:21t-22c-23c
Frame kit#75654 - Mifflin Saunders Frame, b. c. 1806 - 1861 DYF399X:21t-22c-23c
Ingham kit#83351 - James Ingham, b. c. 1829 - Ribchester, Lancashire, UK DYF399X:21t-22c-23c
Frame kit#129873 - James Frame, b. c. 1760 - United Kingdom DYF399X:21t-23c-23c
Frame kit#136903 - Thomas Frame, b. c.1852 - 1893 - Scotland DYF399X:21t-23c-24c
Fraim kit#87806 - David Fraim - Ireland DYF399X:22t-22c-23c
Frame kit#76423 - John Frame, b. c.1785 - Scotland DYF399X:22t-22c-23c
Frame kit#145324 - James 'Irish Jimmy' Frame, b. c.1729 - Scotland DYF399X:22t-22c-23c
Frame kit#150485 - James 'Irish Jimmy' Frame, b. c.1729 - Scotland DYF399X:23t-22c-23c
Frame kit#89177 - James Frame, m. 1801 - Montgomery Co., KY, US DYF399X:22t-22c-23c
Frame kit#163068 - William Frame, b. c.1786 DYF399X:22t-22c-23c
Scruggs kit#16435 - Edward Scruggs, b. c. 1770 - Cumberland Co., VA, US DYF399X:22t-22c-23c
Prophit kit#146708 - James Prophet, b. c. 1783 DYF399X:22t-22c-22c
Etheredge kit#184436 - George Etheredge, b. c. 1751 - England DYF399X:23t-22c-23c
Dutch Group:
Van der Vloet kit#208365 DYF399X:23t-22c-23c
Control Sample:
Salles Fernandes (non-21,21 AS generic) kit#172172 DYF399X:23t-22c-26c
Other non-21,21 AS generics:
MacIsaac (non-21,21 AS generic) kit#182064 DYF399X:21t-23c-23c
Renouf (non-21,21 AS generic) kit#146414 DYF399X:21t-23c-25c
Hendrix (non-21,21 AS generic) kit#40638 DYF399X:22t-22c-26c
Wieder (non-21,21 AS generic) ysearch#5H344 DYF399X:24t-23t-22c-23c
Bemus (non-21,21 AS generic) kit#29143 DYF399X:22t-24c-23c
Uncertain if related 21,21's (likely separate recLOH events):
Slack kit#151617 DYF399X:20t-23c-27c
Slack kit#126651 DYF399X:20t-23c-25c
Gaus kit#57430 DYF399X:23t-22c-26c
Skinnerup kit#136503 DYF399X:23t-23c-23c
Not related:
Ellis (non-21,21 ASgeneric) kit#170911 DYF399X:24t-24c-25c
Ellis (non-21,21 ASgeneric) kit#197362 DYF399X:24t-24c-25c
Ellis (non-21,21 AS generic) kit#108458 DYF399X:24t-24c-25c