Jewish R-M124 Haplogroup

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Jeffrey Paull

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BIG Y Results as of February 15, 2015

Here is a summary of the three Jewish R-M124 BIG Y results to date (one each from Jewish Groups A1, A2, and A3). These results

show that Eastern European Ashkenazi Groups A1 and A2 are closely related, and diverged from Mizrachi Group A3 perhaps 1000-1500

years ago. After this split occurred, these groups continued to develop their own unique SNPs. The number of unique SNPs can be used to

approximate the dates of lineage divergence.

The first group of SNPs labeled "R2 F1758 Jewish Lineage" were found in all three BIG Y tests and indicate these SNPs are common

to Groups A1, A2, and A3. They occurred before the groups diverged and are possibly downstream from F1758 (since there are also
several non-Jewish F1758 FTDNA results from the Middle East that may not share these SNPs).

The second group labeled "R2 F1758 Ashkenazi A1/A2" were found in both the A1 and A2 test results, but not in A3, so are likely to be
common to Groups A1 and A2. They probably occurred after A1 and A2 diverged from A3.

The third group labeled "R2 F1758 Ashkenazi A1 Only" were found only in A1 and are possibly unique to that group. They probably occurred

after the divergence of A1 and A2. If you are in Group A1 you may want to consider ordering one or more of the SNPs in green (specifically
FGC13195, FGC13214, and FGC13223 - these are available as custom order SNPs from FTDNA).

The fourth group labeled "R2 F1758 Ashkenazi A2 Only" were found only in A2 and are possibly unique to that group.They probably occurred

after the divergence of A1 and A2. If you are in Group A2 you may want to consider ordering one or more of the SNPs in green (specifically
A691 - this is available as a custom order SNP from FTDNA).

The fifth group labeled "R2 F1758 Mizrachi A3 Only" were found only in A3 and are possibly unique to that group. They probably occurred in A3

after the divergence of A1 and A2 from A3. These SNPs are not available as custom orders and there is not enough information known yet to
make any recommendations on these SNPs or to request that they be made available for test.

SNPs shown in red are located in problematic regions of the Y chromosome, but are shown below for completeness as they were reported as
derived in BIG Y test results.

Position = GRCh37/hg19 reference location of the SNP

SNP Name = name of the SNP if it has been assigned one

Type of SNP = category of SNP as per the definitions above

Reference = value of the SNP according to the reference sequence (usually the non-mutated "ancestral" value and signified by a - sign)

Genotype = value of the SNP when different than the reference sequence (usually a mutated "derived" value and signified by a + sign)

Position	SNP Name	Type of SNP	Reference	Genotype

7067020	FGC13188	R2 F1758 Jewish Lineage	C	T
7418910	YFS105310	R2 F1758 Jewish Lineage	T	C
7545025	YFS105311	R2 F1758 Jewish Lineage	C	T
7743812	FGC13189	R2 F1758 Jewish Lineage	C	T
8138271	YFS105314	R2 F1758 Jewish Lineage	T	A
8465489	FGC13190	R2 F1758 Jewish Lineage	G	T
8589834	FGC13191	R2 F1758 Jewish Lineage	T	G
8807973	FGC13192	R2 F1758 Jewish Lineage	A	G
9017400	FGC13193	R2 F1758 Jewish Lineage	A	G
9028552	FGC13194	R2 F1758 Jewish Lineage	C	A
9376826	[Problematic]	R2 F1758 Jewish Lineage	G	T
9516323	FGC13196	R2 F1758 Jewish Lineage	A	G
10034929	FGC13198	R2 F1758 Jewish Lineage	C	G
13509408	FGC13199	R2 F1758 Jewish Lineage	G	A
13679170	FGC13200	R2 F1758 Jewish Lineage	A	C
13703988	[ZS5359]	R2 F1758 Jewish Lineage	A	C
14045987	FGC13202	R2 F1758 Jewish Lineage	T	C
14146121	FGC13203	R2 F1758 Jewish Lineage	A	G
14884113	FGC13204	R2 F1758 Jewish Lineage	G	A
14971896	YFS105406	R2 F1758 Jewish Lineage	C	T
15327211	FGC13206	R2 F1758 Jewish Lineage	C	T
15610309	FGC13207	R2 F1758 Jewish Lineage	C	T
15650169	FGC13208	R2 F1758 Jewish Lineage	G	A
15725277	FGC13209	R2 F1758 Jewish Lineage	T	A
15966810	FGC13212	R2 F1758 Jewish Lineage	G	A
15971875	FGC13213	R2 F1758 Jewish Lineage	G	A
16611917	FGC13215	R2 F1758 Jewish Lineage	C	T
17054896	YFS105436	R2 F1758 Jewish Lineage	T	C
17056328	FGC13216	R2 F1758 Jewish Lineage	A	C
17137201	FGC13217	R2 F1758 Jewish Lineage	G	A
17396785	FGC13218	R2 F1758 Jewish Lineage	G	A
17445345	FGC13219	R2 F1758 Jewish Lineage	T	G
17579850	FGC13220	R2 F1758 Jewish Lineage	G	C
17681789	FGC13221	R2 F1758 Jewish Lineage	A	G
17959110	FGC13222	R2 F1758 Jewish Lineage	C	T
19567486	FGC13224	R2 F1758 Jewish Lineage	G	C
21142959	FGC13227	R2 F1758 Jewish Lineage	A	C
21451058	FGC13228	R2 F1758 Jewish Lineage	A	G
21750908	FGC13229	R2 F1758 Jewish Lineage	T	C
21780257	FGC13230	R2 F1758 Jewish Lineage	G	A
21936969	FGC13231	R2 F1758 Jewish Lineage	C	T
21982486	FGC13233	R2 F1758 Jewish Lineage	G	A
22469089	[Problematic]	R2 F1758 Jewish Lineage	G	T
22472828	[FGC13236]	R2 F1758 Jewish Lineage	G	T
22472960	[Problematic]	R2 F1758 Jewish Lineage	T	A
22485986	[Problematic]	R2 F1758 Jewish Lineage	C	A
22488578	[Problematic]	R2 F1758 Jewish Lineage	G	C
22669379	FGC13237	R2 F1758 Jewish Lineage	C	G
22723456	FGC13238	R2 F1758 Jewish Lineage	T	C
23370137	FGC13239	R2 F1758 Jewish Lineage	G	A
23461064	FGC13240	R2 F1758 Jewish Lineage	G	A
23559025	FGC13241	R2 F1758 Jewish Lineage	T	C
23596582	FGC13242	R2 F1758 Jewish Lineage	C	T
24378103	FGC13243	R2 F1758 Jewish Lineage	G	A
24399568	FGC13244	R2 F1758 Jewish Lineage	G	A

2690893	FGC13184	R2 F1758 Ashkenazi A1/A2	G	C
2729943	FGC13185	R2 F1758 Ashkenazi A1/A2	C	T
2871850	FGC13186	R2 F1758 Ashkenazi A1/A2	A	G
5409850	FGC13187	R2 F1758 Ashkenazi A1/A2	A	C
9727099	FGC13197	R2 F1758 Ashkenazi A1/A2	C	T
13683735	FGC13201	R2 F1758 Ashkenazi A1/A2	A	T
15209326	FGC13205	R2 F1758 Ashkenazi A1/A2	T	C
15818166	FGC13210	R2 F1758 Ashkenazi A1/A2	T	C
15908340	FGC13211	R2 F1758 Ashkenazi A1/A2	A	T
20362511	FGC13225	R2 F1758 Ashkenazi A1/A2	G	A
21090871	FGC13226	R2 F1758 Ashkenazi A1/A2	C	A
21973478	FGC13232	R2 F1758 Ashkenazi A1/A2	G	A

9485615	FGC13195	R2 F1758 Ashkenazi A1 Only	A	G
15990243	FGC13214	R2 F1758 Ashkenazi A1 Only	G	T
18062902	FGC13223	R2 F1758 Ashkenazi A1 Only	C	T
22256471	[FGC13234]	R2 F1758 Ashkenazi A1 Only	T	C
22444637	[FGC13235]	R2 F1758 Ashkenazi A1 Only	G	A

7730230	A691	R2 F1758 Ashkenazi A2 Only	T	C
23196937	A692	R2 F1758 Ashkenazi A2 Only	A	T

8038770		R2 F1758 Mizrachi A3	T	C
13677199		R2 F1758 Mizrachi A3	G	T
13806092		R2 F1758 Mizrachi A3	T	A
14282599		R2 F1758 Mizrachi A3	T	A
18250852		R2 F1758 Mizrachi A3	C	T
18545511		R2 F1758 Mizrachi A3	C	G
20814216		R2 F1758 Mizrachi A3	C	T
22147821		R2 F1758 Mizrachi A3	T	C

Jewish R-M124 Haplogroup

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