T subclade discovery

This project is to explore mtDNA haplogroup T and its subgroups except those already defined as T1 and T2.

If you belong to subclade T2, please join the T2 project instead

If you belong to subclade T1, please join the T1 project instead

If you have a full sequence test FMS and are still assigned to T with no subgroup, then submitting your sequence to GenBank is the best option. We also recommend filling the Survey in your account (for mtFull-tests) so that FTDNA's research groups can use your results. See below for details.

Some T are wrongfully assigned, and in reality belong to T1 or T2 with unusual markers. If you suspect this, try to contact FTDNA to let them have another look.

Subclades and Coding Region results

The T-project will assign members to subclades according to these research results. However, without the full mitochondrial sequence (FMS) results it may not be possible to put your results into a subgrouping other than T. If you have done a Full Sequence test (FMS) it is helpful for us if you open up your Coding Region results to be viewed by project administrators. It is your choice whether you permit us to look at your FMS results, but these are most often necessary to assign you to subclades. Only in very rare cases do these reveal any potential medical issues, and most testers choose to include these for mitochondrial DNA-project administrators. Your results, of course, will remain absolutely confidential.

To open the Coding Region results:

1. log in with your kit number and password
2. go to Manage Personal Information and the tab called: Privacy & Sharing
3. find the T-project on the list
4. tick/check the box to show CR-results for the -project
5. click "save" at the bottom of the page

Information about your ancestry

mtDNA is inherited strictly through the direct maternal line.

To learn more about the origins of the various subclades of mt-haplogroup T, it is important that all T-members fill in their ancestral information under Plot Ancestral Location. Enter full name, appr years of birth/death, place, county and country. If unknown because of adoptions or other, please explain under "maternal ancestor" in "User Preferences". Also note that your direct maternal ancestor is the name of your mother's mother's mother etc, through a female line only - it is always a woman. Please also plot the location of this direct maternal ancestor on the map.

We will be updating the "country of origin" if entered in your user information on the mtDNA results webpage. If you have questions, feel free to contact the group administrators.


Research and Resources


Connecting to other mtDNA T members

There is a Facebook mtDNA T-discussion group where anyone can sign up, share and ask questions.


List of Articles

Pike DA, Barton TJ, Bauer SL, Kipp E. 2010. "mtDNA Haplogroup T Phylogeny Based on Full Mitochondrial Sequences". Journal of Genetic Genealogy 6 (1).



Contribute to Research

Have you done the Full Mitochondrial Sequence (FMS)? Are you still “just” T, T1, T2 – or other udefined groups? Maybe no one has done any research on just your specific mtDNA mutations yet.

For the scientists to evaluate all possible SNPs found in your sequence and define new haplogroups/subclades, they need access to more data.

a) Donate to GenBank

Everyone with a Full Sequence test (FMS, FGS, Full, “Mega”) can donate resultats to GenBank and contribute to research.

How?

You need to log in and download your mtDNA results as FASTA-file.
Send it to Ian Logan, who will help you to continue the process.

Detailed description here: Ian Logan's website.

b) Donate your sequence to mtDNA-research via FTDNA

Testers who have done the mtDNA full sequence test (FMS) at FTDNA are asked to fill in a “New Survey”.

Fill in countries of origin, languages etc for your ancestors.

If you already donated to GenBank please also fill in GenBank accession number.

Then they ask permission to use your results in research of new haplogroups, and to be allowed to release your sequence with national origin to the public GenBank database. This happens if they use your sequence in a future scientific paper.

Why?

You will contribute to the discovery of further subclades of mt-DNA.
Results will be accessible to researchers worldwide. Your results are anonymous, only the contact person at GenBank/FTDNA will know who you are.

Behar et al published a paper in 2012 based on donated sequences.